Anaesthesia and oxidative stress in dogs with mitral valve degeneration

The doctoral dissertation of Katerina Tomsič was set out to evaluate whether anaesthesia with propofol, which is believed to have antioxidant properties, causes less oxidative stress in comparison to anaesthesia with propofol and sevoflurane in dogs in which oxidative stress is present due to the myxomatous mitral valve degeneration (MMVD). Anaesthesia with propofol and sevoflurane resulted in increased oxidative stress in dogs with MMVD in comparison to dogs without MMVD, however both anaesthetic protocols can safely be used in dogs with early stage MMVD.

The results of the research were published in two internationally recognized journals: 

• BMC Veterinary Research
• Acta Veterinaria Beograd

Authors

Katerina Tomsič, University of Ljubljana, Veterinary Faculty
Alenka Seliškar, University of Ljubljana, Veterinary Faculty
Alenka Nemec Svete, University of Ljubljana, Veterinary Faculty
Ana Nemec, University of Ljubljana, Veterinary Faculty
Aleksandra Domanjko Petrič, University of Ljubljana, Veterinary Faculty
Tatjana Pirman, University of Ljubljana, Biotechnical Faculty
Vida Rezar, University of Ljubljana, Biotechnical Faculty
Tomaž Vovk, University of Ljubljana, Faculty of Pharmacy